Electrocardiology

Over 50 years of research into automated ECG interpretation

The Electrocardiology Section develops the Glasgow Program for automated ECG analysis, provides ECG Core Laboratory services for research studies, and conducts research into electrocardiographic methods. Our work, led by Professor Peter Macfarlane, has been adopted internationally and contributes to clinical guidelines.

Glasgow Royal Infirmary, New Lister Building
20M+
ECGs interpreted annually
424
Publications
77
h-index
53K+
Citations
Research Output

The Glasgow Program

The Glasgow Program is an automated ECG interpretation system based on careful scientific research, with unique approaches to ECG analysis developed over 50 years of continuous development.

  • Age and Sex Based Criteria Extensive use of age and sex-specific reference ranges, valid from birth through adulthood including neonatal ECGs.
  • Racial Variation Race-based diagnostic criteria accounting for documented differences in ECG amplitudes across populations.
  • Clinical Context Optional integration of clinical diagnosis and drug therapy information to improve interpretation accuracy.
  • Serial Comparison Compare ECGs over time to detect evolving changes, critical for monitoring and research studies.

Adopted by Leading Manufacturers

The Glasgow Program is licensed to medical device manufacturers internationally through the University of Glasgow.

Draeger
Since 1981
Spacelabs Healthcare
Since 1990s
Mindray
Since 2000s
Physio-Control (Stryker)
Since 2000s
BPL Medical Technologies
Since 2010s
Mediana
Since 2010s
Vitalograph
Since 2000s
Edan Instruments
Since 2010s
Compliance: IEC 60601-2-51 (ECG analysis requirements) · IEC 60601-2-25 (Electrocardiograph requirements) · ISO 9001:2015 (Quality management)

Current & Recent Studies

Epidemiological
AIRWAVEScottish Family Health StudyWhitehall II Phase 12
Collaborative
British Regional Heart StudyTromso StudyLeiden 85+ELSA Study (Brazil)Moli Sani
COVID-Related
COVID-HEARTCISCO-19
ISO 9001:2015 Certified
Quality management systems certification, assessed annually since 2003. UKAS accredited.
Clinical Trials Support

ECG Core Laboratory

The ECG Core Lab provides centralised electrocardiogram processing and interpretation for research studies, with ISO 9001:2015 certification maintained since 2003.

ECG Data Management Secure storage and retrieval of study ECGs in electronic and paper formats. Database systems supporting endpoint determination and serial comparison.
Automated Interpretation ECG interpretation using the Glasgow Program with reports reviewed by experienced staff.
Blinded Measurements Independent, blinded ECG measurement and interpretation for research endpoints.
Quality Feedback Feedback to study centres on ECG recording quality and data accuracy.

Research & Publications

Our research into automated ECG interpretation has resulted in numerous peer-reviewed publications and contributions to international guidelines.

Selected Publications

Methodology of ECG interpretation in the Glasgow program

Macfarlane PW, Devine B, Latif S, McLaughlin S, Shoat DB, Watts MP

Methods Inf Med, 1990

Evolution of the Glasgow program for computer-assisted reporting of electrocardiograms—1964/1998

Macfarlane PW

Acta Cardiol, 1998

Evaluation of the electrocardiographic criteria for left ventricular hypertrophy

Macfarlane PW et al.

J Electrocardiol, 2007

Demonstrated Glasgow-modified Romhilt-Estes score superiority

Localization of accessory pathways in the Wolff-Parkinson-White pattern

Macfarlane PW et al.

J Electrocardiol, 2007

Validation of WPW localisation algorithm

424
Publications
77
h-index
53K+
Citations
Including publications in Nature Communications, Circulation, The Lancet, and Journal of Electrocardiology

Books

Comprehensive Electrocardiology
Springer · 2nd Edition

Clinical Guidelines

Research from the Electrocardiology Section has contributed to ESC, ACC, and AHA guidelines for acute myocardial infarction diagnosis criteria.